BDBM14349 2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bromo-4-(carboxymethyl)benzen-1-olate::CRA-9678

SMILES NC(=[NH2+])c1ccc2[nH]c(cc2c1)-c1cc(CC(O)=O)cc(Br)c1[O-]

InChI Key InChIKey=VIZNZQTZRMTYPZ-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14349   

TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14349(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  43nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14349(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  50nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14349(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  290nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14349(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  370nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed