BDBM14353 2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-yl}-4-(dimethylcarbamoyl)-6-phenylbenzen-1-olate::CRA-14316

SMILES CN(C)C(=O)c1cc(-c2cc3cc(C(N)=[NH2+])c(F)cc3[nH]2)c([O-])c(c1)-c1ccccc1

InChI Key InChIKey=QEWPWXLSDLXYFF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14353   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14353(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-...)
Affinity DataKi:  30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14353(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-...)
Affinity DataKi:  130nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14353(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-...)
Affinity DataKi:  650nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14353(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-...)
Affinity DataKi:  3.60E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed