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BDBM145877 US9682960, EM-9114

SMILES: CC1(C)N(CCCOc2ccc(cn2)-c2ccncc2)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=YEEVLPHBCFPKGU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145877   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Mus musculus)
BDBM145877
PNG
(US9682960, EM-9114)
Show SMILES CC1(C)N(CCCOc2ccc(cn2)-c2ccncc2)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F
Show InChI InChI=1S/C26H22F3N5O3/c1-25(2)23(35)34(20-6-4-18(15-30)21(14-20)26(27,28)29)24(36)33(25)12-3-13-37-22-7-5-19(16-32-22)17-8-10-31-11-9-17/h4-11,14,16H,3,12-13H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/a7.425



ENDORECHERCHE, INC.

US Patent


Assay Description
Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...


US Patent US9682960 (2017)


BindingDB Entry DOI: 10.7270/Q2PZ5708
More data for this
Ligand-Target Pair