BDBM14701 2-Cyano-3-(9-ethyl-9H-carbazol-3-ylamino)acrylic Acid Ethyl Ester::ethyl (2Z)-2-cyano-3-[(9-ethyl-9H-carbazol-3-yl)amino]prop-2-enoate::tricyclic compound 6

SMILES CCOC(=O)C(C=Nc1ccc2n(CC)c3ccccc3c2c1)C#N

InChI Key InChIKey=ZCSFFBZXCQGHRG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14701   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Leeds

LigandPNGBDBM14701(2-Cyano-3-(9-ethyl-9H-carbazol-3-ylamino)acrylic A...)
Affinity DataKi:  50nM ΔG°:  -9.95kcal/mole IC50:  440nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Leeds

LigandPNGBDBM14701(2-Cyano-3-(9-ethyl-9H-carbazol-3-ylamino)acrylic A...)
Affinity DataKi:  6.04E+4nM IC50:  4.91E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed