BDBM14975 N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3-{[3-(pyrimidin-4-yl)pyridin-2-yl]amino}benzamide::pyridinyl pyrimidine 40

SMILES COc1ccc(cc1NC(=O)c1ccc(C)c(Nc2ncccc2-c2ccncn2)c1)C(F)(F)F

InChI Key InChIKey=VHCQYUCVMXQFBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14975   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14975(N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3...)
Affinity DataIC50:  58nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM14975(N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3...)
Affinity DataIC50:  43nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed