BDBM14986 N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)benzamide::N-(5-cyclohexyl-2-methoxyphenyl)-4-methyl-3-({3-[2-(methylamino)pyridin-4-yl]pyridin-2-yl}oxy)benzamide::pyridinyl pyridine 49

SMILES CNc1cc(ccn1)-c1cccnc1Oc1cc(ccc1C)C(=O)Nc1cc(ccc1OC)C1CCCCC1

InChI Key InChIKey=XKBVARCCCUFGJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14986   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14986(N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-...)
Affinity DataIC50: >2.50E+4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM14986(N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-...)
Affinity DataIC50:  62nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed