BDBM150975 US8981106, 165::USRE47267, Compound 165

SMILES OB(O)c1ccccc1CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1O

InChI Key InChIKey=AWJICKRJDXZSSC-UHFFFAOYSA-N

Data  2 IC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150975   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150975(US8981106, 165 | USRE47267, Compound 165)
Show SMILES OB(O)c1ccccc1CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1O
Show InChI InChI=1S/C19H16BFN2O4S/c21-14-6-7-16(17(24)9-14)23-19(25)12-5-8-18(22-10-12)28-11-13-3-1-2-4-15(13)20(26)27/h1-10,24,26-27H,11H2,(H,23,25)
Affinity DataIC50: 37nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150975(US8981106, 165 | USRE47267, Compound 165)
Show SMILES OB(O)c1ccccc1CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1O
Show InChI InChI=1S/C19H16BFN2O4S/c21-14-6-7-16(17(24)9-14)23-19(25)12-5-8-18(22-10-12)28-11-13-3-1-2-4-15(13)20(26)27/h1-10,24,26-27H,11H2,(H,23,25)
Affinity DataIC50: 37nMT: 2°CAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...More data for this Ligand-Target Pair