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BDBM152095 US8987474, RPM219

SMILES: CCc1ccccc1N\N=C1/C(=O)Nc2ccc(cc12)S(O)(=O)=O

InChI Key: InChIKey=GIIOECXXSWWQLL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152095   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 11


(Homo sapiens (Human))
BDBM152095
PNG
(US8987474, RPM219)
Show SMILES CCc1ccccc1N\N=C1/C(=O)Nc2ccc(cc12)S(O)(=O)=O
Show InChI InChI=1S/C16H15N3O4S/c1-2-10-5-3-4-6-13(10)18-19-15-12-9-11(24(21,22)23)7-8-14(12)17-16(15)20/h3-9,18H,2H2,1H3,(H,17,19,20)(H,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.65E+4n/an/an/an/an/an/a



University of South Florida

US Patent


Assay Description
NSC-87877 ranked among top 10% (175th) of the compounds with the best GLIDE scores for the docking to the human Shp2 PTP domain in our virtual screen...


US Patent US8987474 (2015)


BindingDB Entry DOI: 10.7270/Q2ZS2V61
More data for this
Ligand-Target Pair