BDBM152699 (S)-2-Amino-5-propionimidamidopentanoic acid (8)::hDDAH inhibitor, 1d

SMILES CCC(=N)NCCC[C@H](N)C(O)=O

InChI Key InChIKey=ZYIBCZWVLDODOL-LURJTMIESA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152699   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM152699((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...)
Affinity DataKi:  7.25E+3nM IC50:  1.61E+4nMpH: 7.4Assay Description:The assay mixture contained L-arginine (10 μM), NADPH (100 μM), oxyhemoglobin (0.125 mg/mL), tetrahydrobiopterin (10 μM), and differen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University

LigandPNGBDBM152699((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...)
Affinity DataKi:  1.45E+5nM ΔG°:  -5.44kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair