BDBM152699 (S)-2-Amino-5-propionimidamidopentanoic acid (8)::hDDAH inhibitor, 1d
SMILES CCC(=N)NCCC[C@H](N)C(O)=O
InChI Key InChIKey=ZYIBCZWVLDODOL-LURJTMIESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 152699
Affinity DataKi: 7.25E+3nM IC50: 1.61E+4nMpH: 7.4Assay Description:The assay mixture contained L-arginine (10 μM), NADPH (100 μM), oxyhemoglobin (0.125 mg/mL), tetrahydrobiopterin (10 μM), and differen...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University
Christian-Albrechts-University
Affinity DataKi: 1.45E+5nM ΔG°: -5.44kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair