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BDBM152751 3-((5-bromo-6-methyl-2-(4-methylpiperidin-1-yl)pyrimidin-4-yl)thio)-6-methyl-8-(4-methylpiperidin-1-yl)-5H-pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (5c)

SMILES: CC1CCN(CC1)c1nc(C)c(C)c(Sc2nnc3Sc4nc(nc(C)c4Nn23)N2CCC(C)CC2)n1

InChI Key: InChIKey=OWZNISSGKKLQPX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152751   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoxygenase-1


(Glycine max (soybean))
BDBM152751
PNG
(3-((5-bromo-6-methyl-2-(4-methylpiperidin-1-yl)pyr...)
Show SMILES CC1CCN(CC1)c1nc(C)c(C)c(Sc2nnc3Sc4nc(nc(C)c4Nn23)N2CCC(C)CC2)n1
Show InChI InChI=1S/C25H34N10S2/c1-14-6-10-33(11-7-14)22-26-17(4)16(3)20(28-22)36-24-30-31-25-35(24)32-19-18(5)27-23(29-21(19)37-25)34-12-8-15(2)9-13-34/h14-15,32H,6-13H2,1-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/a7.025



Ferdowsi University of Mashhad



Assay Description
Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp...


Chem Biol Drug Des 85: 216-24 (2015)


Article DOI: 10.1111/cbdd.12375
BindingDB Entry DOI: 10.7270/Q2ST7NK5
More data for this
Ligand-Target Pair