BDBM155096 US9000182, 5, isomer 1

SMILES CC1=N[C@@]2(N=C1N)c1cc(Br)ccc1C[C@@]21CC[C@H](O)CC1

InChI Key InChIKey=CLOXVWLCRWFUQF-KBRIMQKVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 155096   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM155096(US9000182, 5, isomer 1)
Affinity DataIC50:  96nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM155096(US9000182, 5, isomer 1)
Affinity DataIC50:  270nMpH: 2.5Assay Description:The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human (3-Secretase (AA 1-AA 460) was clone...More data for this Ligand-Target Pair
In DepthDetails US Patent