BDBM15510 (4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-4-(2,4,5-trifluorophenyl)-piperidin-2-one::(4R,5R)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one::4, 5-trans -5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-4-(2, 4, 5-trifluorophenyl)piperidin-2-one::Piperidinone-Constrained Phenethylamine 25::Piperidinone-Constrained Phenethylamine 31::Racemic mixture

SMILES N[C@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F

InChI Key InChIKey=DIRIFWIKLRTNMB-DYVFJYSZSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 15510   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15510((4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)eth...)
Affinity DataKi:  3.20nM ΔG°:  -11.5kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15510((4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)eth...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15510((4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)eth...)
Affinity DataKi:  7.10nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15510((4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)eth...)
Affinity DataKi: >3.00E+3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15510((4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)eth...)
Affinity DataKi: >3.00E+3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed