BDBM15800 Macrocyclic BACE inhibitor 2::tert-butyl N-[(3S,6S,13S)-13-[(1S)-3-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1-hydroxypropyl]-3-methyl-2,5-dioxo-1,4-diazacyclotridecan-6-yl]carbamate

SMILES CC(C)[C@H](NC(=O)CC[C@H](O)[C@@H]1CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N1)C(=O)NCc1ccccc1

InChI Key InChIKey=KIWFHZCVNIKJRF-FVCDFAAQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15800   

TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM15800(Macrocyclic BACE inhibitor 2 | tert-butyl N-[(3S,6...)
Affinity DataIC50:  9.70E+3nMpH: 4.6 T: 2°CAssay Description:The substrate is linked to a fluorescent dye on one end and to a quenching group on its other end. The fluorescence of the substrate is significantly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed