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BDBM15832 1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methyl}-N-{[1-(propan-2-yl)piperidin-4-yl]methyl}-1H-indole-2-carboxamide::2-carboxyindole-based inhibitor 17

SMILES: CC(C)N1CCC(CNC(=O)c2cc3ccccc3n2Cc2cc(on2)-c2ccc(Cl)s2)CC1

InChI Key: InChIKey=OYIDOIKTXHNHIG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15832   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM15832
PNG
(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Show SMILES CC(C)N1CCC(CNC(=O)c2cc3ccccc3n2Cc2cc(on2)-c2ccc(Cl)s2)CC1
Show InChI InChI=1S/C26H29ClN4O2S/c1-17(2)30-11-9-18(10-12-30)15-28-26(32)22-13-19-5-3-4-6-21(19)31(22)16-20-14-23(33-29-20)24-7-8-25(27)34-24/h3-8,13-14,17-18H,9-12,15-16H2,1-2H3,(H,28,32)
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MMDB

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Similars

Article
PubMed
161 -9.26n/an/an/an/an/a7.825



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...


Bioorg Med Chem Lett 14: 4197-201 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.019
BindingDB Entry DOI: 10.7270/Q2610XKM
More data for this
Ligand-Target Pair