BDBM158436 US9029399, 9A::US9339501, 9A

SMILES COc1cc(ccn1)N1CCN(C1=O)c1cnccc1C1CC1

InChI Key InChIKey=PNHAORYXCSBTBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 158436   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM158436(US9029399, 9A | US9339501, 9A)
Affinity DataIC50:  42nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Novartis

US Patent
LigandPNGBDBM158436(US9029399, 9A | US9339501, 9A)
Affinity DataIC50:  4.60nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM158436(US9029399, 9A | US9339501, 9A)
Affinity DataIC50:  42nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Novartis

US Patent
LigandPNGBDBM158436(US9029399, 9A | US9339501, 9A)
Affinity DataIC50:  4.60nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In DepthDetails US Patent