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BDBM159198 US9034866, 675

SMILES: Cc1cc(no1)[C@](C)(O)C#Cc1ccc2OCCc3cc(nn3-c2c1)C(N)=O

InChI Key: InChIKey=KMFXYYBVRWQPMV-HXUWFJFHSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159198   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 14


(Homo sapiens (Human))
BDBM159198
PNG
(US9034866, 675)
Show SMILES Cc1cc(no1)[C@](C)(O)C#Cc1ccc2OCCc3cc(nn3-c2c1)C(N)=O
Show InChI InChI=1S/C20H18N4O4/c1-12-9-18(23-28-12)20(2,26)7-5-13-3-4-17-16(10-13)24-14(6-8-27-17)11-15(22-24)19(21)25/h3-4,9-11,26H,6,8H2,1-2H3,(H2,21,25)/t20-/m1/s1
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PC sid
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Similars

US Patent
6.60n/an/an/an/an/an/a7.2n/a



Genentech Inc

US Patent


Assay Description
The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...


US Patent US9034866 (2015)


BindingDB Entry DOI: 10.7270/Q2GX49B0
More data for this
Ligand-Target Pair