BDBM16096 2-[(6-bromonaphthalene-2-)amido]benzoic acid::2-{[(6-bromonaphthalen-2-yl)carbonyl]amino}benzoic acid::Inhibitor 4
SMILES OC(=O)c1ccccc1NC(=O)c1ccc2cc(Br)ccc2c1
InChI Key InChIKey=KNVPXLPBRSRJCV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 16096
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Leeds
University Of Leeds
Affinity DataKi: 1.10E+3nM ΔG°: -8.12kcal/mole IC50: 8.40E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Leeds
University Of Leeds
Affinity DataKi: 1.64E+4nM ΔG°: -6.52kcal/mole IC50: 1.43E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Leeds
University Of Leeds
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of Plasmodium falciparum HIs6-tagged DHODH expressed in Escherichia coli DH5alpha using L-dihydroorotate as substrate by DCIP-based spectr...More data for this Ligand-Target Pair