BDBM16170 2-(4-chloro-7-{[1-(morpholin-4-ylcarbonyl)cyclopentyl]sulfamoyl}isoquinolin-1-yl)guanidine::cycloleucine deriv. 44

SMILES [#7]\[#6](-[#7])=[#7]/c1ncc(Cl)c2ccc(cc12)S(=O)(=O)[#7]C1([#6]-[#6]-[#6]-[#6]1)[#6](=O)-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1

InChI Key InChIKey=UGFABUVNULNZNU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16170   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16170(2-(4-chloro-7-{[1-(morpholin-4-ylcarbonyl)cyclopen...)
Affinity DataKi:  1.60nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16170(2-(4-chloro-7-{[1-(morpholin-4-ylcarbonyl)cyclopen...)
Affinity DataKi: >3.00E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16170(2-(4-chloro-7-{[1-(morpholin-4-ylcarbonyl)cyclopen...)
Affinity DataKi:  3.44E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed