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BDBM16176 3-(1-adamantyl)-1-[(4-carbamimidamidophenyl)methyl]urea::3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methyl]urea::AGB::WX293T

SMILES: [#7]\[#6](-[#7])=[#7]\c1ccc(-[#6]-[#7]-[#6](=O)-[#7]C23[#6]-[#6]-4-[#6]-[#6](-[#6]-[#6](-[#6]-4)-[#6]2)-[#6]3)cc1

InChI Key: InChIKey=YQPLKJCBEOVDBS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16176   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM16176
PNG
(3-(1-adamantyl)-1-[(4-carbamimidamidophenyl)methyl...)
Show SMILES NC(N)=Nc1ccc(CNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1
Show InChI InChI=1S/C19H27N5O/c20-17(21)23-16-3-1-12(2-4-16)11-22-18(25)24-19-8-13-5-14(9-19)7-15(6-13)10-19/h1-4,13-15H,5-11H2,(H4,20,21,23)(H2,22,24,25)
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PC cid
PC sid
UniChem

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Article
PubMed
2.40E+3 -7.66n/an/an/an/an/a8.025



Max-Planck-Institut fuer Biochemie



Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...


J Mol Biol 301: 465-75 (2000)


Article DOI: 10.1006/jmbi.2000.3966
BindingDB Entry DOI: 10.7270/Q2445JRM
More data for this
Ligand-Target Pair
Trypsin


(Bos taurus (bovine))
BDBM16176
PNG
(3-(1-adamantyl)-1-[(4-carbamimidamidophenyl)methyl...)
Show SMILES NC(N)=Nc1ccc(CNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1
Show InChI InChI=1S/C19H27N5O/c20-17(21)23-16-3-1-12(2-4-16)11-22-18(25)24-19-8-13-5-14(9-19)7-15(6-13)10-19/h1-4,13-15H,5-11H2,(H4,20,21,23)(H2,22,24,25)
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KEGG

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PC cid
PC sid
UniChem

Patents

Article
PubMed
4.60E+4 -5.91n/an/an/an/an/a8.025



Max-Planck-Institut fuer Biochemie



Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...


J Mol Biol 301: 465-75 (2000)


Article DOI: 10.1006/jmbi.2000.3966
BindingDB Entry DOI: 10.7270/Q2445JRM
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (human))
BDBM16176
PNG
(3-(1-adamantyl)-1-[(4-carbamimidamidophenyl)methyl...)
Show SMILES NC(N)=Nc1ccc(CNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1
Show InChI InChI=1S/C19H27N5O/c20-17(21)23-16-3-1-12(2-4-16)11-22-18(25)24-19-8-13-5-14(9-19)7-15(6-13)10-19/h1-4,13-15H,5-11H2,(H4,20,21,23)(H2,22,24,25)
PDB
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PC cid
PC sid
UniChem

Patents

Article
PubMed
>1.00E+6>-4.09n/an/an/an/an/a8.025



Max-Planck-Institut fuer Biochemie



Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...


J Mol Biol 301: 465-75 (2000)


Article DOI: 10.1006/jmbi.2000.3966
BindingDB Entry DOI: 10.7270/Q2445JRM
More data for this
Ligand-Target Pair