BDBM16317 3-({5-cyano-6-[(2,2-dimethylpropyl)(methyl)amino]-2-(4-methyl-1,4-diazepan-1-yl)pyrimidin-4-yl}amino)-N-methoxy-4-methylbenzamide::5-Cyanopyrimidine Derivative 2

SMILES CONC(=O)c1ccc(C)c(Nc2nc(nc(N(C)CC(C)(C)C)c2C#N)N2CCCN(C)CC2)c1

InChI Key InChIKey=UONISFJXHMSTQN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16317   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM16317(3-({5-cyano-6-[(2,2-dimethylpropyl)(methyl)amino]-...)
Affinity DataKi:  0.0570nM ΔG°:  -13.8kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed