BDBM1633 2-ethyl-10-methyl-2,4,10-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-one::Pyridobenzodiazepinone deriv. 11

SMILES CCN1c2ccccc2N(C)C(=O)c2cccnc12

InChI Key InChIKey=QIBWCUCLHZVYNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1633   

TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM1633(2-ethyl-10-methyl-2,4,10-triazatricyclo[9.4.0.0^{3...)
Affinity DataIC50:  350nMAssay Description:Inhibition of HIV1 reverse transcriptase derived from HIV patient plasma by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM1633(2-ethyl-10-methyl-2,4,10-triazatricyclo[9.4.0.0^{3...)
Affinity DataIC50:  350nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed