BDBM16457 6-[(5-chloro-1-benzofuran-2-)sulfonyl]-2,3-dihydropyridazin-3-one::CHEMBL240722::Heterocyclic Sulfonylpyridazinone, 19i::benzofuran, 23

SMILES Clc1ccc2oc(cc2c1)S(=O)(=O)c1ccc(=O)[nH]n1

InChI Key InChIKey=ZDIDXSOYTUCPQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16457   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16457(6-[(5-chloro-1-benzofuran-2-)sulfonyl]-2,3-dihydro...)
Affinity DataIC50:  25nMAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16457(6-[(5-chloro-1-benzofuran-2-)sulfonyl]-2,3-dihydro...)
Affinity DataIC50:  25nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16457(6-[(5-chloro-1-benzofuran-2-)sulfonyl]-2,3-dihydro...)
Affinity DataIC50:  25nMpH: 7.0 T: 2°CAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed