BDBM16486 2-{6-phenyl-3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]-1H-indol-1-yl}acetic acid::Indoleacetic Acid Inhibitor 42

SMILES OC(=O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccc(cc12)-c1ccccc1

InChI Key InChIKey=OTPMXLDHDYTZCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16486   

TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16486(2-{6-phenyl-3-[(4,5,7-trifluoro-1,3-benzothiazol-2...)
Affinity DataIC50:  6.10E+3nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16486(2-{6-phenyl-3-[(4,5,7-trifluoro-1,3-benzothiazol-2...)
Affinity DataIC50:  25nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed