BDBM165396 US8168651, Compound TABLE 16.64::US9062043, Table 13, Compound 100::US9062043, Table 13, Compound 64::US9062043, Table 20b, Compound 29

SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(c1)C(F)(F)F)c1nc(NC3CC3)ncc21

InChI Key InChIKey=UXZATHOFDZQOMY-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 165396   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM165396(US8168651, Compound TABLE 16.64 | US9062043, Table...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM165396(US8168651, Compound TABLE 16.64 | US9062043, Table...)
Affinity DataIC50:  9nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM165396(US8168651, Compound TABLE 16.64 | US9062043, Table...)
Affinity DataIC50: >750nMpH: 7.2Assay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM165396(US8168651, Compound TABLE 16.64 | US9062043, Table...)
Affinity DataIC50:  9nMpH: 7.2Assay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair