BDBM17084 3-chloro-N-{2-[(4-fluorophenyl)carbamoyl]-4-methylphenyl}-1-benzothiophene-2-carboxamide::anthranilamide compound 1

SMILES Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)c(c1)C(=O)Nc1ccc(F)cc1

InChI Key InChIKey=FBPXLHRHDPRVOH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17084   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17084(3-chloro-N-{2-[(4-fluorophenyl)carbamoyl]-4-methyl...)
Affinity DataKi:  10nM ΔG°:  -10.8kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17084(3-chloro-N-{2-[(4-fluorophenyl)carbamoyl]-4-methyl...)
Affinity DataKi:  11nMAssay Description:Inhibition constant against human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17084(3-chloro-N-{2-[(4-fluorophenyl)carbamoyl]-4-methyl...)
Affinity DataKi:  11nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM17084(3-chloro-N-{2-[(4-fluorophenyl)carbamoyl]-4-methyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition constant against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM17084(3-chloro-N-{2-[(4-fluorophenyl)carbamoyl]-4-methyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition constant against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed