BDBM17101 3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carbamoyl]-6-methoxyphenyl}-4-{[(2-hydroxy-2-methylpropyl)(methyl)amino]methyl}thiophene-2-carboxamide::Thiophene-Anthranilamide, 10m

SMILES COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)CC(C)(C)O)c1Cl

InChI Key InChIKey=FDWVHQKXWFKPKP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17101   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17101(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  0.710nM ΔG°:  -12.3kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17101(3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...)
Affinity DataKi:  1.10E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed