BDBM17182 (3S)-3-(4-{[3-(2-chloro-4-{[(2-methylphenyl)carbamoyl]amino}phenyl)-2-oxo-1,2-dihydropyridin-1-yl]methyl}phenyl)butanoic acid::Pyridone derivative, 28

SMILES C[C@@H](CC(O)=O)c1ccc(Cn2cccc(-c3ccc(NC(=O)Nc4ccccc4C)cc3Cl)c2=O)cc1

InChI Key InChIKey=ZSKXPSIETQZQJF-FQEVSTJZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17182   

TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM17182((3S)-3-(4-{[3-(2-chloro-4-{[(2-methylphenyl)carbam...)
Affinity DataKi:  25.1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed