BDBM172639 US9090628, 299

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(C)c(cc3-c2n1)[C@@H](C)N1CCN(CC1)C(C)(C)C

InChI Key InChIKey=ROEMKOMVFBZVIY-HXUWFJFHSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 172639   

LigandPNGBDBM172639(US9090628, 299)
Affinity DataKi:  0.480nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM172639(US9090628, 299)
Affinity DataIC50:  0.479nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM172639(US9090628, 299)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed