BDBM17279 2-(5-carbamimidoyl-2-hydroxyphenoxy)-6-[3-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pyridine-4-carboxylic acid::CHEMBL315014::Pyridine template, IV::ZK-806688
SMILES NC(=N)c1ccc(O)c(Oc2cc(cc(Oc3cccc(c3)C3=NCCN3)n2)C(O)=O)c1
InChI Key InChIKey=KDDSLUYCOZXRQI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 17279
Affinity DataKi: 85nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
Affinity DataKi: 85nM ΔG°: -9.54kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
Affinity DataKi: 85nM ΔG°: -9.54kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibitory constant against bovine trypsin for general specificity against serine proteasesMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nM ΔG°: -7.90kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 1.40E+3nM ΔG°: -7.90kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibitory potency was measured against bovine trypsin.More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory potency was measured against human thrombinMore data for this Ligand-Target Pair