BDBM175250 US9115140, I-118

SMILES COc1ccccc1-c1c(sc2cnc(Nc3cc(C)c(cc3OC(C)C)N3CCC(C3)N(C)C)nc12)C(N)=O

InChI Key InChIKey=MSPKZWJUTCZYAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175250   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM175250(US9115140, I-118)
Affinity DataIC50:  2nMAssay Description:The reagents used have the following composition: Enzyme buffer (EB): 50 mM HEPES (pH: 7.0) (Sigma H7523), 100 mM NaCl (Sigma S7653), NaN.sub.3 at 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM175250(US9115140, I-118)
Affinity DataIC50:  2nMAssay Description:The reagents used have the following composition: Enzyme buffer (EB): 50 mM HEPES (pH: 7.0) (Sigma H7523), 100 mM NaCl (Sigma S7653), NaN.sub.3 at 0....More data for this Ligand-Target Pair
In DepthDetails US Patent