BDBM176745 US9675612, 1 6-{[2-(Cyclopropylmethyl)[1,3]thiazolo[5,4-d]pyrimidin-7-yl]amino}-1,3-benzothiazol-2(3H)-one

SMILES O=c1[nH]c2ccc(Nc3ncnc4sc(CC5CC5)nc34)cc2s1

InChI Key InChIKey=KVTOGWASAODVEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176745   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM176745(US9675612, 1 6-{[2-(Cyclopropylmethyl)[1,3]thiazol...)
Affinity DataIC50:  37nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent