BDBM176774 US9675612, 17 2-(2-Phenylethyl)-N-[6-(propan-2-yloxy)-1H-indazol-5-yl][1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES CC(C)Oc1cc2[nH]ncc2cc1Nc1ncnc2sc(CCc3ccccc3)nc12

InChI Key InChIKey=FTJIPXCJVBZCBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176774   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM176774(US9675612, 17 2-(2-Phenylethyl)-N-[6-(propan-2-ylo...)
Affinity DataIC50:  229nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent