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BDBM180381 US9133168, Example 37c::US9133168, Example 38c

SMILES: CC1Cc2c(ccc(F)c2Cl)N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1

InChI Key:

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 180381   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM180381
PNG
(US9133168, Example 37c | US9133168, Example 38c)
Show SMILES CC1Cc2c(ccc(F)c2Cl)N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...


US Patent US9133168 (2015)


BindingDB Entry DOI: 10.7270/Q29W0D8X
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM180381
PNG
(US9133168, Example 37c | US9133168, Example 38c)
Show SMILES CC1Cc2c(ccc(F)c2Cl)N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 7n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...


US Patent US9133168 (2015)


BindingDB Entry DOI: 10.7270/Q29W0D8X
More data for this
Ligand-Target Pair