BDBM181073 (E)-N'-(3-bromobenzylidene)-4-(2-oxo-2H-chromen-3-yl)thiazole-2-carbohydrazide (7r)

SMILES Brc1cccc(\C=N\NC(=O)c2nc(cs2)-c2cc3ccccc3oc2=O)c1

InChI Key InChIKey=LBNFOQAQBGEAFZ-LSHDLFTRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181073   

TargetProbable maltase-glucoamylase 2(Homo sapiens)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM181073((E)-N'-(3-bromobenzylidene)-4-(2-oxo-2H-chrome...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitro phenyl glucopyranoside as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Jishou University

LigandPNGBDBM181073((E)-N'-(3-bromobenzylidene)-4-(2-oxo-2H-chrome...)
Affinity DataIC50:  1.40E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed