BDBM181573 US9139577, 4.079::US9708274, 4.079

SMILES C[C@@H](Oc1cc(Cl)ccc1Nc1ncnc2cc(cc(C)c12)N=S1(=O)CCC1)C(=O)N[C@@H](C)C(F)(F)F

InChI Key InChIKey=KDWRBWAZGYAENZ-CABCVRRESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181573   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM181573(US9139577, 4.079 | US9708274, 4.079)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM181573(US9139577, 4.079 | US9708274, 4.079)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent