BDBM18167 4-(Tetrahydro-7-hydroxy-1,3-dioxo-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl)-1-1,3(2H)-dione::7-hydroxy-2-(4-nitronaphthalen-1-yl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidine-1,3-dione::N-aryl-bicyclic hydantoin, (+/-)10a

SMILES OC1CCn2c1c(O)n(-c1ccc([N+]([O-])=O)c3ccccc13)c2=O

InChI Key InChIKey=VVPBWVARDNMMID-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18167   

TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18167(4-(Tetrahydro-7-hydroxy-1,3-dioxo-1H-pyrrolo[1,2-c...)
Affinity DataKi:  3.5nM ΔG°:  -11.4kcal/mole EC50:  4.40nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed