BDBM18174 4-[(7R,7aR)-7-hydroxy-3-oxo-hexahydro-1H-pyrrolo[1,2-a]imidazolidin-2-yl]-2-chloro-3-methylbenzonitrile::JMC522794 Compound 2::imidazolin-2-one, 8
SMILES [H][C@]12CN(C(=O)N1CC[C@H]2O)c1ccc(C#N)c(Cl)c1C
InChI Key InChIKey=INWVYYLEFLPGMU-VXGBXAGGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 18174
Affinity DataKi: 2nM ΔG°: -11.7kcal/mole EC50: 15nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -11.1kcal/mole EC50: 6.40nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair