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BDBM183444 US9145354, 42

SMILES: CC[C@@H](N)c1ccc(Cl)c(C(=O)c2cc[n+]([O-])cc2)c1F

InChI Key: InChIKey=WDIPXHCWEYNWGC-GFCCVEGCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183444   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM183444
PNG
(US9145354, 42)
Show SMILES CC[C@@H](N)c1ccc(Cl)c(C(=O)c2cc[n+]([O-])cc2)c1F
Show InChI InChI=1S/C15H14ClFN2O2/c1-2-12(18)10-3-4-11(16)13(14(10)17)15(20)9-5-7-19(21)8-6-9/h3-8,12H,2,18H2,1H3/t12-/m1/s1
PDB
MMDB

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Similars

US Patent
n/an/a 530n/an/an/an/an/a25



Astex Therapeutics Limited

US Patent


Assay Description
The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...


US Patent US9145354 (2015)


BindingDB Entry DOI: 10.7270/Q2VH5MMZ
More data for this
Ligand-Target Pair