BDBM18363 (2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidine-3,4,5-triol::CO-DNJ::alpha-1-C-Octyl-DNJ

SMILES CCCCCCCC[C@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=IIHXPVAHXKBRBL-RKQHYHRCSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18363   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)
Affinity DataKi:  280nM ΔG°:  -9.29kcal/mole IC50:  500nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat intestinal isomaltase using isomoltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)
Affinity DataIC50:  5.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed