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BDBM183928 US9150526, 186

SMILES: COc1cc(C)cc(OC)c1-c1cncc(c1)C(CC(O)=O)c1nnc(C)o1

InChI Key: InChIKey=KUUYGXCCHWNUHC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183928   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin A (CTSA)


(Homo sapiens (Human))
BDBM183928
PNG
(US9150526, 186)
Show SMILES COc1cc(C)cc(OC)c1-c1cncc(c1)C(CC(O)=O)c1nnc(C)o1
Show InChI InChI=1S/C20H21N3O5/c1-11-5-16(26-3)19(17(6-11)27-4)14-7-13(9-21-10-14)15(8-18(24)25)20-23-22-12(2)28-20/h5-7,9-10,15H,8H2,1-4H3,(H,24,25)
PDB
MMDB

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 343n/an/an/an/a6.037



Sanofi

US Patent


Assay Description
Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h...


US Patent US9150526 (2015)


BindingDB Entry DOI: 10.7270/Q2QR4VXP
More data for this
Ligand-Target Pair