BDBM18595 6-[(thiophen-2-ylmethyl)(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::6-bisalkylamino-2-quinolinone, 6t

SMILES FC(F)(F)CN(Cc1cccs1)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key InChIKey=KQHQCOMIOSNTPU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18595   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18595(6-[(thiophen-2-ylmethyl)(2,2,2-trifluoroethyl)amin...)
Affinity DataKi:  61nM ΔG°:  -10.2kcal/mole EC50:  12nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed