BDBM18628 (18Z)-12-methoxy-3,5,5-trimethyl-18-{[3-(2,2,2-trifluoro-1-hydroxyethyl)thiophen-2-yl]methylidene}-17-oxa-6-azatetracyclo[8.8.0.0^{2,7}.0^{11,16}]octadeca-1(10),2(7),3,8,11,13,15-heptaen-13-ol::secondary alcohol, 15
SMILES COc1c(O)ccc2O\C(=C/c3sccc3C(O)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12
InChI Key InChIKey=MJQKPIOTILTXNU-ODLFYWEKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 18628
Affinity DataKi: 1.40nM ΔG°: -11.2kcal/mole IC50: 0.400nM EC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 670nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 1.78E+3nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair