BDBM18675 (2S)-2-hydroxy-3-(4-isothiocyanatophenoxy)-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide::BMC146525 arylisothiocyanato derivative, S-23::Nonsteroidal AR Ligand, S-16

SMILES CC(O)(COc1ccc([N-]C#[S+])cc1)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=SJWMTXJQSDNMAN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18675   

TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Tennessee Health Science Center

LigandPNGBDBM18675((2S)-2-hydroxy-3-(4-isothiocyanatophenoxy)-2-methy...)
Affinity DataKi:  4.60nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Tennessee Health Science Center

LigandPNGBDBM18675((2S)-2-hydroxy-3-(4-isothiocyanatophenoxy)-2-methy...)
Affinity DataKi:  4.62nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed