BDBM18696 (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-3-[(3-isothiocyanatophenyl)sulfanyl]-2-methylpropanamide::Bicalutamide Analogue, (S)-8

SMILES C[C@@](O)(CSc1cccc(c1)N=C=S)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=TWMKHPVCLNCRKT-GOSISDBHSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18696   

TargetAndrogen receptor(Rattus norvegicus (Rat))
Csc-Scientific Computing

Curated by ChEMBL
LigandPNGBDBM18696((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydro...)
Affinity DataKi:  129nMAssay Description:Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Csc-Scientific Computing

Curated by ChEMBL
LigandPNGBDBM18696((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydro...)
Affinity DataKi:  130nM ΔG°:  -8.73kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed