BDBM1876 1-(2-phenylethyl)-3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]thiourea::N-(2-Phenethyl)-N -(2-(4-(trifluoromethyl)thiazolyl))thiourea::PETT Analog 43

SMILES FC(F)(F)c1csc(NC(=S)NCCc2ccccc2)n1

InChI Key InChIKey=PIOSJSRPZNUBFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1876   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1876(1-(2-phenylethyl)-3-[4-(trifluoromethyl)-1,3-thiaz...)
Affinity DataIC50:  550nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed