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BDBM188568 US9169246, 67

SMILES: CCn1c2cc(ccc2c2[nH]ncc2c1=O)-c1ccc(nc1)N1CCNCC1

InChI Key: InChIKey=JCDULRXTCADBBB-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188568   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM188568
PNG
(US9169246, 67)
Show SMILES CCn1c2cc(ccc2c2[nH]ncc2c1=O)-c1ccc(nc1)N1CCNCC1
Show InChI InChI=1S/C21H22N6O/c1-2-27-18-11-14(3-5-16(18)20-17(21(27)28)13-24-25-20)15-4-6-19(23-12-15)26-9-7-22-8-10-26/h3-6,11-13,22H,2,7-10H2,1H3,(H,24,25)
PDB
MMDB

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Similars

US Patent
n/an/a 22.9n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...


US Patent US9169246 (2015)


BindingDB Entry DOI: 10.7270/Q2B856XZ
More data for this
Ligand-Target Pair