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BDBM189173 US9169270, 45

SMILES: OC(=O)COc1ccc(Cl)cc1C1N(CCc2ncsc12)C(=O)\C=C\c1ccccc1

InChI Key: InChIKey=NOFUKEBGADAVFU-RMKNXTFCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189173   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM189173
PNG
(US9169270, 45)
Show SMILES OC(=O)COc1ccc(Cl)cc1C1N(CCc2ncsc12)C(=O)\C=C\c1ccccc1
Show InChI InChI=1S/C23H19ClN2O4S/c24-16-7-8-19(30-13-21(28)29)17(12-16)22-23-18(25-14-31-23)10-11-26(22)20(27)9-6-15-4-2-1-3-5-15/h1-9,12,14,22H,10-11,13H2,(H,28,29)/b9-6+
PDB

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Similars

US Patent
n/an/a 59.6n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 μl. First, 25 μl of test compound, previously diluted in Binding-Buffer (Binding...


US Patent US9169270 (2015)


BindingDB Entry DOI: 10.7270/Q22R3QFG
More data for this
Ligand-Target Pair