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BDBM191589 6-(pyridin-3-yl)pteridine-2,4,7-triamine (33)

SMILES: Nc1nc(N)c2nc(c(N)nc2n1)-c1cccnc1

InChI Key: InChIKey=MOSVRUOQBNLXAK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191589   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase I delta/epsilon


(Homo sapiens (Human))
BDBM191589
PNG
(6-(pyridin-3-yl)pteridine-2,4,7-triamine (33))
Show SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccnc1
Show InChI InChI=1S/C11H10N8/c12-8-6(5-2-1-3-15-4-5)16-7-9(13)18-11(14)19-10(7)17-8/h1-4H,(H6,12,13,14,17,18,19)
PDB

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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.55E+4n/an/an/an/a7.5n/a



Max Planck Institute of Molecular Physiology



Assay Description
A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...


Cell Chem Biol 23: 494-507 (2016)


Article DOI: 10.1016/j.chembiol.2016.02.015
BindingDB Entry DOI: 10.7270/Q2GQ6WJD
More data for this
Ligand-Target Pair
Casein kinase I isoform delta


(Homo sapiens (Human))
BDBM191589
PNG
(6-(pyridin-3-yl)pteridine-2,4,7-triamine (33))
Show SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccnc1
Show InChI InChI=1S/C11H10N8/c12-8-6(5-2-1-3-15-4-5)16-7-9(13)18-11(14)19-10(7)17-8/h1-4H,(H6,12,13,14,17,18,19)
PDB

Reactome pathway

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.61E+4n/an/an/an/a7.5n/a



Max Planck Institute of Molecular Physiology



Assay Description
A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...


Cell Chem Biol 23: 494-507 (2016)


Article DOI: 10.1016/j.chembiol.2016.02.015
BindingDB Entry DOI: 10.7270/Q2GQ6WJD
More data for this
Ligand-Target Pair