BDBM192298 US9187450, 45::US9321747, 19

SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCCCS(C)(=O)=O)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1

InChI Key InChIKey=PBBIETQWWVEHHA-ZQAZVOLISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192298   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192298(US9187450, 45 | US9321747, 19)
Affinity DataIC50:  13nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192298(US9187450, 45 | US9321747, 19)
Affinity DataIC50:  22.9nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 μg) and 5,5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192298(US9187450, 45 | US9321747, 19)
Affinity DataIC50:  18.9nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 μg) and 5,5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192298(US9187450, 45 | US9321747, 19)
Affinity DataIC50:  10nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 μg) and 5,5...More data for this Ligand-Target Pair
In DepthDetails US Patent