BDBM19550 (2S)-4-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-methylphenyl)formamido]butanamide::arylaminoethyl amide, 5d

SMILES COc1ccc(NCCNC(=O)[C@H](CCC2CCCCC2)NC(=O)c2cccc(C)c2)cc1

InChI Key InChIKey=MNECACXIBPFIKN-VWLOTQADSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19550   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19550((2S)-4-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  38nM ΔG°:  -10.5kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19550((2S)-4-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  326nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19550((2S)-4-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed